Bot. 423 GENETICS III (2+3): 3

Bot. 423 GENETICS III (2+3): 3

Molecular genetics: Physical, chemical and biological evidence that DNA is the genetic material, the genetic dogma. Structures of DNA and RNAs: Macro and micro organization of the genetic material in prokaryotes and eukaryotes. Gene Mutations: Types of mutations, mutagenic agents, mechanism of action of some mutagens, classification of mutations at the molecular level, some aspects of the environmental effects of mutagens and their importance. Replication of DNA: Replication in prokaryotes, eukaryotes and some models for replication of viral genetic material. DNA Repair: Repair of errors of replication and mutations, revertants in genetic analysis. Gene Expression: Regulation of Gene Expression in prokaryotes and eukaryotes. Introduction to recombinant DNA technology.